MOST PRESCRIBED
Top Sellers
Tirzepatide/Pyridoxine
Dual GIP/GLP-1 agonist for appetite regulation and weight management.
Semaglutide/Pyridoxine
GLP-1 receptor agonist for appetite suppression and metabolic support.
Sermorelin
Foundational GH-axis peptide for sleep, recovery, and energy.
NAD+
Cellular energy and longevity support.
PT-141 (Bremelanotide)
Enhances sexual desire through brain receptor pathways.
GHK-Cu
Copper peptide for skin rejuvenation and tissue repair.
Glutathione
Master antioxidant for detoxification and cellular health.
Protocol Comparison
Semaglutide vs. Tirzepatide
A clear, side-by-side look at how the two most prescribed weight-loss peptides compare across function, mechanism, and projected outcomes.
| Feature | Semaglutide | Tirzepatide |
|---|---|---|
| What It Does | A GLP-1 receptor agonist that mimics the GLP-1 hormone to suppress appetite, slow gastric emptying, and improve blood sugar control, supporting weight loss through reduced calorie intake. | A dual GIP + GLP-1 receptor agonist that combines appetite suppression with improved insulin sensitivity and glucose regulation, targeting weight loss through multiple metabolic pathways. |
| How They Differ | Single-mechanism approach — acts on the GLP-1 receptor pathway alone. | Dual-mechanism approach — acts on both the GIP and GLP-1 receptor pathways. |
| Mechanism of Action | GLP-1 (glucagon-like peptide-1) receptor agonist — mimics the GLP-1 incretin hormone, reducing appetite, slowing digestion, and enhancing insulin secretion. | GIP + GLP-1 dual receptor agonist — combines GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 activity for greater appetite suppression and glucose control. |
| Projected Weight Loss (Public Reports) | Approximately 15% average body weight reduction at higher doses (STEP trials, ~68 weeks). | Approximately 20–22% average body weight reduction at the highest dose (SURMOUNT trials, ~72 weeks). |
Weight-loss projections are based on publicly available community reports and individual results vary. Not a guarantee of outcome. Peptides require a physician-issued prescription.
WHY AION
Let us help you be your best.
The current healthcare system is reactive — it treats disease after it appears. But aging, hormonal decline, and metabolic dysfunction start long before symptoms show. Let our physicians guide you from day one.
Hormones, genetics, stress, environment, and metabolism can make traditional approaches feel impossible.
Hormones
Testosterone, thyroid, and growth hormone decline with age — silently affecting energy, libido, and body composition.
Genetics
Your DNA shapes how you respond to diet, exercise, and medication. One-size-fits-all approaches ignore this.
Stress & Environment
Chronic stress, poor sleep, and environmental toxins disrupt your endocrine system and accelerate aging.
Metabolism
Metabolic dysfunction underlies weight gain, fatigue, and chronic disease. GLP-1s and peptides can restore balance.
50%
of NAD+ is lost by age 60
Cellular energy declines with age.
1 in 4
men have low testosterone
Often undiagnosed and untreated.
70%
of adults are metabolically unhealthy
GLP-1 therapy can change that.
YOUR JOURNEY
Three simple steps to better health.
From intake to delivery, we've made proactive healthcare simple, affordable, and physician-supervised.
Complete Your Intake
Select your desired Rx, share your health goals, symptoms, and medical history through our secure online portal. Takes about 5 minutes — no insurance needed.
Physician Review & Protocol
A Prescribery licensed physician reviews your intake and/or lab results, then designs a personalized treatment protocol using GLP-1s, peptides, or hormone optimization. Note, physicians may decline a request if you're not eligible due to your medical history.
COMMON QUESTIONS